An overview of arteriosclerosis
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Excess cholesterol in the bloodstream is a major cause of arteriosclerosis. Cholesterol builds up on the walls of bloodvessels, forming atherosclerotic plaque.
Blood vessels become more prone to clogging, and may be lead to issues such as: cardiac infarction, cerebral infarction/ stroke and aortic aneurysm.
Test Method and Results
Trials using arteriosclerotic model on mice
Either normal feed alone or a mixture of feed and bunapi (3%) was given to mice that are genetically disposed to developing arteriosclerosis for a period of 10 weeks. (Five mice per group.)
The heart and surrounding blood vessels of the mice
The suppression of atherosclerotic plaque with bunapi
Area painted with green; atherosclerotic lesion
The reduction of cholesterol levels due to bunapi
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We conclude that bunapi can be expected to lower blood cholesterol levels, with the effect of suppressing arteriosclerosis.
Antiatherosclerotic effect of Bunapi / PDF
Hitoshi Ishida, Graduate School of Pharmaceutical Sciences, University of Shizuoka
Masahiko Ikeda, Graduate School of Health Sciences, University of Shizuoka
Mushroom laboratory, HOKUTO Corporation
Published in: Nutrition Research Volume 28, Issue 5, May 2008, Pages 335–342