An overview of arteriosclerosis
Excess cholesterol in the bloodstream is a major cause of arteriosclerosis. Cholesterol builds up on the walls of bloodvessels, forming atherosclerotic plaque.
Blood vessels become more prone to clogging, and may be lead to issues such as: cardiac infarction, cerebral infarction/ stroke and aortic aneurysm.
Test Method and Results
Trials using arteriosclerotic model on mice
Either normal feed alone or a mixture of feed and bunapi (3%) was given to mice that are genetically disposed to developing arteriosclerosis for a period of 10 weeks. (Five mice per group.)
The heart and surrounding blood vessels of the mice
The suppression of atherosclerotic plaque with bunapi
Area painted with green; atherosclerotic lesion
The reduction of cholesterol levels due to bunapi
We conclude that bunapi can be expected to lower blood cholesterol levels, with the effect of suppressing arteriosclerosis.
Hitoshi Ishida, Graduate School of Pharmaceutical Sciences, University of Shizuoka
Masahiko Ikeda, Graduate School of Health Sciences, University of Shizuoka
Mushroom laboratory, HOKUTO Corporation
Published in: Nutrition Research Volume 28, Issue 5, May 2008, Pages 335–342