Pursuing the pharmacological effects and functions of mushrooms with a focus on health.

Our mushroom research center, Mushroom General Research Institute is dedicated to scientifically unraveling the beneficial pharmacological effects of mushrooms in order to put them to use in promoting and maintaining healthy lifestyles. 

We have already advanced research into a wide array of potential beneficial effects of mushrooms. Along with these efforts we are striving to contribute to the life sciences through developing health foods and (functional foods) that feature mushrooms.

The results of our research are shown below.

 
 

List of all our research reports and studies

Article titleJournalVol.,PageYear
Pleurotus eryngii ameliorates lipopolysaccharide-induced lung inflammation in miceEvidence-based complementary and alternative medicine2014, 1-72014
Effects of Hericium erinaceus on amyloid beta(25-35) peptide-induced learning and memory dificits in miceBiomedical research32, 67-722011
Hypolipidemic effect of Pleurotus eryngii extract in fat-loaded miceJ Nutr Sci Vitaminol56, 48-532010
Inhibitory effect of hericenone B from Hericium erinaceus on collagen-induced platelet aggregationPhytomedicine17, 1082-10852010
Rat medium-term multi-organ carcinogenesis bioassay of Agaricus blazei Murrill fruit-body extractFood and chemical toxicology48, 402-4082010
Effects and safety of Pleurotus eryngii on body fat reduction in subjects with a body mass index between 24.5 and 35 kg/m2Jpn Pharmacol Ther38, 645-6572010
Endotoxin contamination of Agaricus blazei Murrill extract enhances murine immunologic responses and inhibits the growth of sarcoma 180 implants in vivoJ Environ Pathol Toxicol Oncol29, 159-1682010
Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: A double-blind placebo-controlled clinical trialPhytother Res23, 367-3722009
Antiatherosclerotic effect of the edible mushrooms Pleurotus eryngii (Eringi), Grifola frondosa (Maitake), and Hypsizygus marmoreus (Bunashimeji) in apolipoprotein E–deficient miceNutrition research28, 335-3422008
Nerve growth factor-inducing activity of Hericium erinaceus in 1321N1 human astrocytoma cellsBiol Pharm bull31, 1727-17322008
Suppressive effect of Pleurotus eryngii extract on postprandial serum triacylglycerol elevation. (Japanese)Jpn Pharmacol Ther36, 817-8232008
Hypotensive effects and safety of extracts squeezed from Agaricus blazei on high-normal blood pressure and mild hypertensive subjects. (Japanese)Jpn Pharmacol Ther34, 1323-13412006
The safety of excessive ingestion of Agaricus blazei in high-normal blood pressure persons. (Japanese)Jpn Pharmacol Ther34, 1311-13212006
Effect of extracts squeezed from Agaricus blazei for high-normal blood bressure or mild hypertension on human blood pressure. (Janapene)Jpn Pharmacol Ther34, 1295-13092006
The safety of normal and excessive ingestion of Agaricus blazei in healthy persons. (Japanese)Jpn Pharmacol Ther34, 1247-12572006
An acute single oral dose toxicity study of a compression extract of Agaricus blazei Murrill fruit-body in rats. (Japanese)Pharmacometrics70, 93-952006
A 90-day repeated oral toxicity study of the compression extract of Agaricus blazei Murrill fruit-body in rats. (Japanese)Pharmacometrics71, 51-592006
Micronucleus test for oral administration of a compression extract of Agaricus blazei Murrill fruit-body with mice. (Japanese)Pharmacometrics71, 47-502006
A 28-day repeat oral toxicity study of a compression extract of Agaricus blazei Murrill fruit-body in rats. (Japanese)Pharmacometrics71, 37-462006